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<p>Esophageal motility disorders comprise a&#xa0;heterogeneous group of conditions, with achalasia being the most well-characterized entity. In addition, spastic disorders such as diffuse esophageal spasm, jackhammer esophagus, and esophagogastric junction outflow obstruction (EGJOO) represent clinically relevant subtypes. Endoscopic treatment options for achalasia include pneumatic dilation (PD), and peroral endoscopic myotomy (POEM), while surgical myotomy remains an alternative. Among these, POEM has emerged as a&#xa0;highly effective and durable minimally invasive technique with excellent clinical success rates. In contrast, the management of nonachalasia spastic motility disorders is less standardized due to limited evidence and disease heterogeneity. POEM has increasingly gained importance in this setting, primarily due to its ability to tailor the length and location of myotomy to the spastic segment. Although clinical outcomes are promising, most data are derived from retrospective studies and small cohorts. Overall, treatment strategies should be individualized based on disease subtype, symptom severity, and patient-specific factors, ideally in specialized centers.</p>

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Endoskopische Therapie von Ösophagusmotilitätsstörungen

  • 期刊论文

  • 发表日期：

    2026年5月21日

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  • Sandra Nagl

摘要

Esophageal motility disorders comprise a heterogeneous group of conditions, with achalasia being the most well-characterized entity. In addition, spastic disorders such as diffuse esophageal spasm, jackhammer esophagus, and esophagogastric junction outflow obstruction (EGJOO) represent clinically relevant subtypes. Endoscopic treatment options for achalasia include pneumatic dilation (PD), and peroral endoscopic myotomy (POEM), while surgical myotomy remains an alternative. Among these, POEM has emerged as a highly effective and durable minimally invasive technique with excellent clinical success rates. In contrast, the management of nonachalasia spastic motility disorders is less standardized due to limited evidence and disease heterogeneity. POEM has increasingly gained importance in this setting, primarily due to its ability to tailor the length and location of myotomy to the spastic segment. Although clinical outcomes are promising, most data are derived from retrospective studies and small cohorts. Overall, treatment strategies should be individualized based on disease subtype, symptom severity, and patient-specific factors, ideally in specialized centers.