Scholarlink

<p>Due to increasing insecticide resistance and environment concerns associated with synthetic chemicals, this study evaluates the larvicidal potential of essential oils (EO) extracted from seven plant species using hydro-distillation against <i>Aedes aegypti</i> larvae. The chemical profiles of the volatile oils were characterized through gas chromatography-mass spectrometry (GC–MS). The major constituents identified were thymol (74.93%) in <i>Plectranthus amboinicus</i> leaves, terpinen-4-ol (27.13%) in <i>Myristica fragrans</i> nuts, citral (27.55%) in <i>Citrus limon</i> leaves, caryophyllene oxide (36.11%) in <i>Hyptis suaveolens</i> leaves, and asarone (85.51%) in <i>Acorus calamus</i> rhizomes. Larvicidal bioassays revealed LC<sub>50</sub> values below 50&#xa0;ppm (23.40 to 47.34&#xa0;ppm), with the order of efficacy being <i>A. calamus</i> &gt; <i>M. fragrans</i> &gt; <i>T. ammi</i> &gt; <i>I. verum</i> &gt; <i>C. limon</i> &gt; <i>H. suaveolens</i> &gt; <i>P. amboinicus</i>. Twenty-one binary and thirty-five ternary combinations were tested to determine synergistic, additive, and antagonistic interactions using Wadley's, Ting-Chao Chou, Co-Toxicity Factor, and Chi-square comparison methods. Binary combinations, such as <i>P. amboinicus</i> and <i>M. fragrans</i> and <i>T. ammi</i> and <i>M. fragrans</i> exhibited better synergism, this combination analysed by GC–MS, <i>P. amboinicus</i> and <i>M. fragrans</i> contains, carvacrol (36.23%), thymol (39.04%), and caryophyllene oxide (3.84%). Similarly, the combination of <i>T. ammi</i> and <i>M. fragrans</i> showed thymol (61.96%) and caryophyllene oxide (7.19%). Based on the EO yield and activity the <i>T. ammi</i> and <i>M. fragrans</i> binary combination formulated as soft-gel capsules, this formulation showed 100% larval mortality. EO mixtures work very well, showing they could be good, eco-friendly options to replace chemical insecticides for controlling mosquito larvae in the future.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Development of an eco-friendly mosquito larvicide for dengue/chikungunya vector control

  • 期刊论文

  • 发表日期：

    2026年5月30日

查看全文
  • Sundharesan Munusamy,
  • Irrusappan Hari,
  • Balamurugan Mookiah,
  • Shriram Ananganallur Nagarajan

摘要

Due to increasing insecticide resistance and environment concerns associated with synthetic chemicals, this study evaluates the larvicidal potential of essential oils (EO) extracted from seven plant species using hydro-distillation against Aedes aegypti larvae. The chemical profiles of the volatile oils were characterized through gas chromatography-mass spectrometry (GC–MS). The major constituents identified were thymol (74.93%) in Plectranthus amboinicus leaves, terpinen-4-ol (27.13%) in Myristica fragrans nuts, citral (27.55%) in Citrus limon leaves, caryophyllene oxide (36.11%) in Hyptis suaveolens leaves, and asarone (85.51%) in Acorus calamus rhizomes. Larvicidal bioassays revealed LC50 values below 50 ppm (23.40 to 47.34 ppm), with the order of efficacy being A. calamus > M. fragrans > T. ammi > I. verum > C. limon > H. suaveolens > P. amboinicus. Twenty-one binary and thirty-five ternary combinations were tested to determine synergistic, additive, and antagonistic interactions using Wadley's, Ting-Chao Chou, Co-Toxicity Factor, and Chi-square comparison methods. Binary combinations, such as P. amboinicus and M. fragrans and T. ammi and M. fragrans exhibited better synergism, this combination analysed by GC–MS, P. amboinicus and M. fragrans contains, carvacrol (36.23%), thymol (39.04%), and caryophyllene oxide (3.84%). Similarly, the combination of T. ammi and M. fragrans showed thymol (61.96%) and caryophyllene oxide (7.19%). Based on the EO yield and activity the T. ammi and M. fragrans binary combination formulated as soft-gel capsules, this formulation showed 100% larval mortality. EO mixtures work very well, showing they could be good, eco-friendly options to replace chemical insecticides for controlling mosquito larvae in the future.