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Background <p>Nanoscale investigations with ordinary optical microscopes require evanescent fields resolution when the target is to go beyond the λ/2 resolution limit. Photon-phonon interactions from quantum mechanics to Newtonian mechanics, explain how traditional microscopy can achieve nanometric accuracy in Experimental Mechanics.</p> Objectives <p>To detail NanoFraction (NF), a digital system that works beyond the limits of traditional optical microscopy.</p> Methods <p>The NF system is an extension of more than two decades of research work by the authors in super-resolution. NF overcomes the λ/2 resolution limit by recording the near-field in the far-field, enabling broader fields of view with unmatched spatial resolution. NF uses lasers with wavelengths between 400 and 700&#xa0;nm to capture images of objects in the nanometer range. Unlike fluorescent super-resolution or cryogenic electron microscopy, NF is a label-free imaging modality. Artificial intelligence (AI) is integral to the NF system.</p> Results <p>The NF system is successfully utilized for nanoscale investigations in chemistry, semi-conductor industry and living organisms such as (i) detection of crystalline structures (i.e. NaCl nano-crystals); (ii) detection of defects in diamond wafers; (iii) detection of COVID-19 virus structures. The article demonstrates how the NF system can be applied to organic materials, such as the COVID-19 virus.</p> Conclusions <p>NF allows to visualize details that were previously only visible with transmission electron microscopy (TEM), but without the limitations of this technique. The NF system has important implications for understanding the nanoworld.</p>

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Digital Holographic Moiré Generalized NanoFraction

  • 期刊论文

  • 发表日期：

    2025年5月30日

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  • C.A. Sciammarella,
  • L. Lamberti,
  • E. Sciammarella,
  • F.M. Sciammarella,
  • L. Santoro

摘要

Background

Nanoscale investigations with ordinary optical microscopes require evanescent fields resolution when the target is to go beyond the λ/2 resolution limit. Photon-phonon interactions from quantum mechanics to Newtonian mechanics, explain how traditional microscopy can achieve nanometric accuracy in Experimental Mechanics.

Objectives

To detail NanoFraction (NF), a digital system that works beyond the limits of traditional optical microscopy.

Methods

The NF system is an extension of more than two decades of research work by the authors in super-resolution. NF overcomes the λ/2 resolution limit by recording the near-field in the far-field, enabling broader fields of view with unmatched spatial resolution. NF uses lasers with wavelengths between 400 and 700 nm to capture images of objects in the nanometer range. Unlike fluorescent super-resolution or cryogenic electron microscopy, NF is a label-free imaging modality. Artificial intelligence (AI) is integral to the NF system.

Results

The NF system is successfully utilized for nanoscale investigations in chemistry, semi-conductor industry and living organisms such as (i) detection of crystalline structures (i.e. NaCl nano-crystals); (ii) detection of defects in diamond wafers; (iii) detection of COVID-19 virus structures. The article demonstrates how the NF system can be applied to organic materials, such as the COVID-19 virus.

Conclusions

NF allows to visualize details that were previously only visible with transmission electron microscopy (TEM), but without the limitations of this technique. The NF system has important implications for understanding the nanoworld.