Scholarlink

Objective <p>To compare heart rate recovery (HRR), rate-pressure product (RPP), and heart rate variability (HRV) between individuals with chronic low back pain (CLBP) and healthy controls following a maximal exercise test, in order to assess autonomic and cardiovascular recovery patterns.</p> Methods <p>A cross-sectional study was conducted with 51 participants divided into two groups: CLBP (n = 23) and controls (n = 28). Participants underwent a maximal treadmill test with continuous heart rate and blood pressure monitoring. HRR was evaluated at 10&#xa0;s, 1, 2, and 3&#xa0;min post-exercise. RPP was calculated at rest, peak effort, and recovery. HRV was analyzed in both time and frequency domains before and after the test. Statistical analyses included Student’s <i>t</i>-test, two-way ANOVA, and Shapiro–Wilk normality tests (<i>p</i> &lt; 0.05).</p> Results <p>The CLBP group showed significantly lower HRR values across all recovery intervals (<i>p</i> &lt; 0.001) and higher RPP at rest, peak effort, and recovery (<i>p</i> &lt; 0.001), indicating increased myocardial workload. HRV indices were consistently lower in the CLBP group compared with controls, both pre- and post-exercise (SDNN: 36.6 ± 3.52 vs. 41.0 ± 3.85&#xa0;ms; RMSSD: 29.5 ± 4.48 vs. 39.8 ± 4.54&#xa0;ms; <i>p</i> &lt; 0.001). Frequency domain analysis revealed reduced LF and HF components and higher LF/HF ratio in the CLBP group.</p> Conclusion <p>CLBP exhibit impaired autonomic regulation, which is characterized by a slower heart rate recovery, reduced heart rate variability, and an increased myocardial workload after maximal exercise. These findings suggest parasympathetic dysregulation and reinforce the need for multidisciplinary interventions that target cardiovascular and autonomic restoration in this population.</p> Highlights <p>Individuals with chronic low back pain show impaired autonomic modulation and slower cardiovascular recovery after maximal exercise.</p> <p>Heart rate recovery and HRV may serve as noninvasive markers of autonomic dysfunction in chronic pain populations.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Dysfunctional autonomic regulation and slower cardiovascular recovery in patients with chronic low back pain after physical maximal effort: cross-sectional study

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月5日

查看全文
  • Denilson Silva Martins,
  • André Pontes-Silva,
  • Yane Pelicer-Marques,
  • Kelerson Mauro de-Castro-Pinto,
  • Nivaldo de Jesus Silva Soares-Junior,
  • Sabrina Marinho Coutinho,
  • Laiza Fernanda Chagas-da-Silva,
  • Cristiano Teixeira Mostarda,
  • Almir Vieira Dibai-Filho,
  • Flávio de Oliveira Pires

摘要

Objective

To compare heart rate recovery (HRR), rate-pressure product (RPP), and heart rate variability (HRV) between individuals with chronic low back pain (CLBP) and healthy controls following a maximal exercise test, in order to assess autonomic and cardiovascular recovery patterns.

Methods

A cross-sectional study was conducted with 51 participants divided into two groups: CLBP (n = 23) and controls (n = 28). Participants underwent a maximal treadmill test with continuous heart rate and blood pressure monitoring. HRR was evaluated at 10 s, 1, 2, and 3 min post-exercise. RPP was calculated at rest, peak effort, and recovery. HRV was analyzed in both time and frequency domains before and after the test. Statistical analyses included Student’s t-test, two-way ANOVA, and Shapiro–Wilk normality tests (p < 0.05).

Results

The CLBP group showed significantly lower HRR values across all recovery intervals (p < 0.001) and higher RPP at rest, peak effort, and recovery (p < 0.001), indicating increased myocardial workload. HRV indices were consistently lower in the CLBP group compared with controls, both pre- and post-exercise (SDNN: 36.6 ± 3.52 vs. 41.0 ± 3.85 ms; RMSSD: 29.5 ± 4.48 vs. 39.8 ± 4.54 ms; p < 0.001). Frequency domain analysis revealed reduced LF and HF components and higher LF/HF ratio in the CLBP group.

Conclusion

CLBP exhibit impaired autonomic regulation, which is characterized by a slower heart rate recovery, reduced heart rate variability, and an increased myocardial workload after maximal exercise. These findings suggest parasympathetic dysregulation and reinforce the need for multidisciplinary interventions that target cardiovascular and autonomic restoration in this population.

Highlights

Individuals with chronic low back pain show impaired autonomic modulation and slower cardiovascular recovery after maximal exercise.

Heart rate recovery and HRV may serve as noninvasive markers of autonomic dysfunction in chronic pain populations.