Evaluation of a sleep sound analysis smartphone app for home obstructive sleep apnea screening among community-dwelling Chinese adults with hypertension
摘要
This study aimed to evaluate the validity and feasibility of home obstructive sleep apnea screening using a sleep sound analysis smartphone app compared to the STOP-BANG questionnaire (SBQ) among Chinese adults with hypertension, including the impact of screening on intention to pursue treatment.
MethodsA randomized cross-over trial was conducted among adults with hypertension from a hospital clinic and community health center in Haikou, China. Participants were assigned to undergo sequential screening with a sleep sound analysis smartphone app (Snail Sleep) or the SBQ followed by home sleep apnea testing. Questionnaires measured satisfaction and intention to pursue treatment.
ResultsAmong 180 participants (median age: 51.0 years, 72.2% male), 91.7% had OSA, including 28.3% with moderate OSA, and 37.2% with severe OSA (mean AHI 28.6, SD = 23.02). An app-generated apnea index (APP-AI) optimal cutoff of 7.1 achieved 72.0% sensitivity, 85.5% specificity, a 4.96 positive likelihood ratio (LR), and a 0.33 negative LR for moderate-to-severe OSA (AHI ≥ 15), with an area under the curve (AUC) of 0.831 (95% CI 0.773–0.89), outperforming the original SBQ (BMI > 35) (AUC 0.728) and modified SBQ (BMI > 28) (AUC 0.754). Participants reported high satisfaction levels. Intention to pursue treatment decreased among those given normal screening results while remaining high among those given abnormal results.
ConclusionA sleep sound analysis smartphone app achieved acceptable validity and feasibility for home OSA screening in a group of Chinese adults with hypertension. Further studies should evaluate app screening in other populations and effects on patient attitudes and behavior.