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Objective <p>To conduct a systematic review and meta-analysis to evaluate long term effect of soft tissue surgery on blood pressure (BP) in adults with obstructive sleep apnea (OSA).</p> Search methods <p>PubMed, Scopus, the Cochrane library, and Ovid Medline databases were searched through January 2024. Manual searches were also obtained. This review included studies assessing impact of soft tissue surgery for the treatment of OSA in adults on long-term BP.</p> Result <p>A total of five studies (299 patients) met our inclusion criteria. Pooled random effects analysis demonstrated a statistically significant long-term postoperative reduction of BP, with average systolic BP reduction of 14.04&#xa0;mmHg [95%CI (-21.97, -6.11); P = 0.0005]. Pooled random effects analysis of data from four studies (277 patients) also demonstrated statistically significant long-term postoperative reduction of diastolic BP by 6.88&#xa0;mmHg compared with preoperative baseline [95%CI (-13.31, -0.45); P = 0.04].</p> Conclusion <p>Soft tissue surgery for OSA treatment in adults significantly resulted in long-term blood pressure reduction.</p>

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Long-term effects on blood pressure of soft tissue surgery for obstructive sleep apnea treatment in adults: a systematic review and meta-analysis

  • 期刊论文

  • 发表日期：

    2025年4月5日

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  • Sirisuit Ruengpolviwat,
  • Prakobkiat Hirunwiwatkul,
  • Natamon Charakorn

摘要

Objective

To conduct a systematic review and meta-analysis to evaluate long term effect of soft tissue surgery on blood pressure (BP) in adults with obstructive sleep apnea (OSA).

Search methods

PubMed, Scopus, the Cochrane library, and Ovid Medline databases were searched through January 2024. Manual searches were also obtained. This review included studies assessing impact of soft tissue surgery for the treatment of OSA in adults on long-term BP.

Result

A total of five studies (299 patients) met our inclusion criteria. Pooled random effects analysis demonstrated a statistically significant long-term postoperative reduction of BP, with average systolic BP reduction of 14.04 mmHg [95%CI (-21.97, -6.11); P = 0.0005]. Pooled random effects analysis of data from four studies (277 patients) also demonstrated statistically significant long-term postoperative reduction of diastolic BP by 6.88 mmHg compared with preoperative baseline [95%CI (-13.31, -0.45); P = 0.04].

Conclusion

Soft tissue surgery for OSA treatment in adults significantly resulted in long-term blood pressure reduction.