International expert consensus statement: surgical failure in obstructive sleep apnea

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2024年9月23日

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Giannicola Iannella,
Annalisa Pace,
Giuseppe Magliulo,
Claudio Vicini,
Rodolfo Lugo,
Olivier M. Vanderveken,
Nico de Vries,
Kenny Pang,
Eric Thuler,
Ofer Jacobowitz,
Michel Burihan Cahali,
Joachim T. Maurer,
Manuele Casale,
Antonio Moffa,
Fabrizio Salamanca,
Federico Leone,
Ewa Olszewska,
Carlos O’connor Reina,
Edilson Zancanella,
Paul T. Hoff,
Peter Baptista,
Ahmed Yassin Bahgat,
Madeline J. L. Ravesloot,
Peter van Maanen,
Andrew Goldberg,
Marina Carrasco,
Vikas K. Agrawal,
Jerome R. Lechien,
Andrea De Vito,
Giovanni Cammaroto,
Armando De Virgilio,
Antonio Greco,
Patrizia Mancini,
Tiziano Perrone,
Steve Amado,
Uri Alkan,
Ryan Chin Taw Cheong,
Aurelio D’Ecclesia,
Dorina Galantai,
Anand RajuAnand,
Christian Calvo-Henriquez,
Salvatore Cocuzza,
Michele Arigliani,
Alberto Maria Saibene,
Rosario Marchese Aragona,
Antonino Maniaci

摘要

Purpose

Upper airway (UA) surgery is commonly employed in the treatment of patients with obstructive sleep apnea (OSA). The intricate pathophysiology of OSA, variability in sites and patterns of UA collapse, and the interaction between anatomical and non-anatomical factors in individual patients may contribute to possible surgical failures. This clinical consensus statement aims to identify areas of agreement among a development group comprising international experts in OSA surgery, regarding the appropriate definition, predictive factors in patients, and management of surgical failure in OSA treatment.

Methods

A clinical consensus statement (CCS) was developed using the Delphi method by a panel of 35 contributors from various countries. A systematic literature review adhering to PRISMA guidelines was conducted. A survey consisting of 60 statements was then formulated and presented to the experts.

Results

Following two rounds of the Delphi process, consensus or strong consensus was achieved on 36 items, while 24 items remained without consensus. Specifically, 5 out of 10 statements reached consensus regarding on the 'Definition of Surgical Success/Failure after OSA Surgery'. Regarding the 'Predictive Factors of Surgical Failure in OSA Surgery', consensus was reached on 10 out of 13 statements. In the context of the 'Diagnostic Workup in OSA Surgery', consensus was achieved on 9 out of 13 statements. Lastly, in 'Treatment in Surgical Failure Cases', consensus was reached on 12 out of 24 statements.

Conclusion

The management of OSA after surgical failure presents a significant clinical challenge for sleep specialists. This CCS provides valuable guidance for defining, preventing, and addressing surgical failures in the treatment of OSA syndrome.