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PDX Models in Theranostic Applications: Generation and Screening for B Cell Lymphoma of Human Origin

  • Shayla Shmuel,
  • Sébastien Monette,
  • Dina Ibrahim,
  • Patrícia M.R. Pereira

摘要

This MIB guide briefly summarizes the generation of patient-derived xenografts (PDXs) and highlights the importance of validating PDX models for the presence of B cell lymphoma of human origin before their use in radiotheranostic applications. The use of this protocol will allow researchers to learn different methods for screening PDX models for Epstein-Barr virus (EBV)-infected B cell lymphoma.