Metabolomics 2023 workshop report: moving toward consensus on best QA/QC practices in LC–MS-based untargeted metabolomics

期刊论文
出版模式：

开放获取
发表日期：

2024年7月9日

查看全文

Jonathan D. Mosley,
Warwick B. Dunn,
Julia Kuligowski,
Matthew R. Lewis,
María Eugenia Monge,
Candice Ulmer Holland,
Dajana Vuckovic,
Krista A. Zanetti,
Tracey B. Schock

摘要

Introduction

During the Metabolomics 2023 conference, the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) presented a QA/QC workshop for LC–MS-based untargeted metabolomics.

Objectives

The Best Practices Working Group disseminated recent findings from community forums and discussed aspects to include in a living guidance document.

Methods

Presentations focused on reference materials, data quality review, metabolite identification/annotation and quality assurance.

Results

Live polling results and follow-up discussions offered a broad international perspective on QA/QC practices.

Conclusions

Community input gathered from this workshop series is being used to shape the living guidance document, a continually evolving QA/QC best practices resource for metabolomics researchers.