Molecular Communication Under Different Signaling Waveforms and Biological Deployments

Every second, millions of cells within our bodies exchange critical messages. Yet, amidst this swarming molecular dialogue, miscommunications often occur, leading to misdiagnosis and ineffective treatments. Over 30% of therapeutic molecules fail to reach their intended targets due to inadequate understanding of tissue communication pathways. Herein, we unveil a novel diffusive molecular communication (DMC) model, offering insights into concentration dynamics and channel responses across diverse tissue geometries. We employed various signaling waveforms to gain insights into how these geometries impact the propagation and reception of molecular signals in tissues under different practical scenarios. In particular, rectangular and exponential signaling waveforms under each biological rectangular deployment, Biological cylindrical deployment, and biological spherical deployments have been used to analyze the DMC system in terms of concentration and channel response. First of all, the concentration of the information signal is derived analytically under each of the signaling waveforms and deployments. Further, the presented concentration of the information signal under each signaling and deployments are employed in evaluating the channel response at the receiver. Each of the presented analytical expressions has been quantified numerically under different parameters. The results demonstrate DMC’s potential for developing new-era targeted drug delivery and bio-sensing technologies.