In the present work, a metamaterial-inspired high gain multiband Circular Microstrip Antenna (CMSA) that facilitates operation at \(2.4\) , \(3\) , \(5\) , \(7.1\) , \(8.45\) , and \(9.9{ }\;{\text{GHz}}\) for wireless communication is designed and illustrated. The antenna configuration consists of an array of crossed Complementary symmetry Split Ring Resonators (CSRR) as a metamaterial structure in the radiating patch that facilitates multiband operation and the meshed ground plane that facilitates high gain and bandwidth operations. A low-cost FR4 epoxy substrate with a thickness of \(1.6{ }\;{\text{mm}}\) is used to fabricate the antenna. The overall structure is analyzed and validated using HFSS (High Frequency Structure Simulator). The simulated and measured results of the proposed antenna structure are in good agreement. The antenna attains a measured − \(10{ }\;{\text{dB }}\left| {{\text{S}}_{11} } \right|\) bandwidth \(210{ }\;{\text{MHz}}\) with an improved gain of \(3.48 \;{\text{dB}}\) and overall \(90\boldsymbol{\%}\) radiation efficiency at the desired resonating frequency of \(2.45{ }\;{\text{GHz}}\) . The designed antenna offers appealing characteristics in the Industry Scientific and Medical (ISM) band and wireless communication applications for other operational bands like WLAN and Wi-MAX.