Scholarlink

<p>Equine infectious anemia (EIA) is a chronic disease caused by the equine infectious anemia virus (EIAV), a member of the <i>Retroviridae</i> family and the <i>Lentivirus</i> genus. Most infected animals are asymptomatic carriers, which makes clinical diagnosis challenging. This study aimed to conduct a clinical and laboratory evaluation of EIA in equids used for equestrian tourism in Jericoacoara National Park, Ceará, Brazil. A total of 112 equids (104 horses and 8 mules) underwent clinical, hematological, biochemical, serological, and molecular assessments. The EIAV seropositivity rates were 11.6% by AGID, 36.6% by gp90 ELISA, and 25.9% by p26 ELISA. Amplified DNA in the tat-gag PCR assay was detected in 23.2% of the samples. Phylogenetic analyses confirmed the genetic diversity of EIAV circulating in Brazil. This diversity may influence immune responses and consequently diagnostic outcomes. A significant correlation was observed between animals seropositive in diagnostic tests for EIAV and the elevated levels of the gamma-glutamyl transferase (GGT) enzyme, suggesting possible subclinical hepatic involvement. The findings reinforce the value of a comprehensive diagnostic strategy and the monitoring of biochemical parameters in seropositive animals, while also highlighting deficiencies in current EIA control measures.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Equine infectious anemia in Brazilian equestrian tourism horses: serological, molecular, and biochemical assessment showing high EIAV seroprevalence and elevated gamma-glutamyl transferase (GGT) levels

  • 期刊论文

  • 发表日期：

    2025年11月27日

查看全文
  • Viviane Maria Dias Costa,
  • Raimundo Nonato de Aguiar Filho,
  • Gissandra Farias Braz,
  • Cahuê Francisco Rosa Paz,
  • Betania Paiva Drumond,
  • Bruno Marques Teixeira,
  • Erna Geessien Kroon

摘要

Equine infectious anemia (EIA) is a chronic disease caused by the equine infectious anemia virus (EIAV), a member of the Retroviridae family and the Lentivirus genus. Most infected animals are asymptomatic carriers, which makes clinical diagnosis challenging. This study aimed to conduct a clinical and laboratory evaluation of EIA in equids used for equestrian tourism in Jericoacoara National Park, Ceará, Brazil. A total of 112 equids (104 horses and 8 mules) underwent clinical, hematological, biochemical, serological, and molecular assessments. The EIAV seropositivity rates were 11.6% by AGID, 36.6% by gp90 ELISA, and 25.9% by p26 ELISA. Amplified DNA in the tat-gag PCR assay was detected in 23.2% of the samples. Phylogenetic analyses confirmed the genetic diversity of EIAV circulating in Brazil. This diversity may influence immune responses and consequently diagnostic outcomes. A significant correlation was observed between animals seropositive in diagnostic tests for EIAV and the elevated levels of the gamma-glutamyl transferase (GGT) enzyme, suggesting possible subclinical hepatic involvement. The findings reinforce the value of a comprehensive diagnostic strategy and the monitoring of biochemical parameters in seropositive animals, while also highlighting deficiencies in current EIA control measures.