Scholarlink

Background <p>Tuberculosis is a zoonotic disease affecting domestic ruminants, human worldwide and caused by <i>Mycobacterium bovis</i> that belongs to <i>Mycobacterium tuberculosis complex</i>. In Chad, tuberculosis caused by <i>Mycobacterium bovis</i> was previously isolated from both suspected patients and domestic ruminant carcass.</p> Objectives <p>The objective of our study is to assess the multispecies feature of causative agents of tuberculosis infection in domestic ruminants destined to human consumption.</p> Methods <p>In 2012, a cross-sectional study was conducted in 7 abattoirs in southern Chad. Bacteriology and molecular typing were performed on collected lesions.</p> Results <p>Samples were taken on suspected lesions carcass from local cattle breeds as 234 Arabic, 91 Fulani, 1 Bogolodje and 1 cross breeds. Among them, 25 were defined as “total seizures” and 302 others as “partial seizures”. These lesions were majority within the age group from 3 to 12 years old. Mainly <i>Mycobacterium bovis</i> strains were isolated from 42 suspected bovine carcasses. <i>Mycobacterium tuberculosis</i> strain was isolated from a female Fulani 6 years old. However, 112 of these carcass were males and 215 females and sex has significant influence on tuberculosis infection in cattle (<i>p</i> = 0, 04, OR = 1, 7 IC OR 95%: 1,039 − 3,089). Thus, females were twice as likely to be at risk as males and ten (3%) suspected cattle carcass were due to Non Tuberculosis Mycobacteria infection.</p> Conclusion <p>As previously show by other studies performed in Chad, causatives agents of lesions suspected in abattoir as tuberculosis lesions are usually diverse. However, <i>M.bovis</i> was confirmed in bovine carcass but <i>M.tuberculosis</i> was also isolated.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

First isolation of Mycobacterium tuberculosis from suspected cases of bovine tuberculosis in rural abattoirs in Chad

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年3月31日

查看全文
  • D. Lamireou,
  • B. N. Ngandolo,
  • P. Koné,
  • S. Tadio,
  • C. Diguimbaye,
  • R. Alambédji,
  • J. Zinsstag,
  • B. Bonfoh

摘要

Background

Tuberculosis is a zoonotic disease affecting domestic ruminants, human worldwide and caused by Mycobacterium bovis that belongs to Mycobacterium tuberculosis complex. In Chad, tuberculosis caused by Mycobacterium bovis was previously isolated from both suspected patients and domestic ruminant carcass.

Objectives

The objective of our study is to assess the multispecies feature of causative agents of tuberculosis infection in domestic ruminants destined to human consumption.

Methods

In 2012, a cross-sectional study was conducted in 7 abattoirs in southern Chad. Bacteriology and molecular typing were performed on collected lesions.

Results

Samples were taken on suspected lesions carcass from local cattle breeds as 234 Arabic, 91 Fulani, 1 Bogolodje and 1 cross breeds. Among them, 25 were defined as “total seizures” and 302 others as “partial seizures”. These lesions were majority within the age group from 3 to 12 years old. Mainly Mycobacterium bovis strains were isolated from 42 suspected bovine carcasses. Mycobacterium tuberculosis strain was isolated from a female Fulani 6 years old. However, 112 of these carcass were males and 215 females and sex has significant influence on tuberculosis infection in cattle (p = 0, 04, OR = 1, 7 IC OR 95%: 1,039 − 3,089). Thus, females were twice as likely to be at risk as males and ten (3%) suspected cattle carcass were due to Non Tuberculosis Mycobacteria infection.

Conclusion

As previously show by other studies performed in Chad, causatives agents of lesions suspected in abattoir as tuberculosis lesions are usually diverse. However, M.bovis was confirmed in bovine carcass but M.tuberculosis was also isolated.