<p>Voltammetric techniques have been widely used in developing analytical methods for antibiotic determination. These techniques are based on the oxidation and/or reduction of antibiotic molecules occurring at the surface of the working electrode. Carbon nanomaterials have been used to modify the working electrode surface to produce an analytical device with enhanced performance. Considering the importance of understanding the electrochemical mechanism of antibiotic molecules on the electrode surface, and the increasing number of authors proposing these reaction mechanisms for carbon nanomaterial-modified electrodes, this review compiles recent reports on the proposed redox mechanisms for selected antibiotics. Key aspects such as the type of carbon nanomaterial, redox potential, supporting electrolyte, and kinetic mechanism involved in these processes are considered. A review was organized in the ScienceDirect^® and Scopus^® databases, using the keywords “determination”, “voltammetry”, name of antibiotic, and combinations of the antibiotic name with “voltammetry”, covering publications from January 2023 to December 2024. Researchers interested in using voltammetric techniques for antibiotic determination will benefit from this review, gaining insights into their redox reaction mechanisms on carbon nanomaterials-based modified working electrodes.</p> Graphical Abstract <p></p>