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Copper (II) complexes with (E)-N(3,5-di-tert-butyl-2-hydroxybenzilidene)-2-hydroxybenzohydrazide, their bactericidal and fungicidal activity

  • Perizad Amrulla Fatullayeva,
  • Ajdar Akper Medjidov,
  • Rayyat Huseyn Ismayilov,
  • Asim Sabri Abdullayev,
  • Sevinc Rafiq Lahicova,
  • Gulu Qanimet Abbasova,
  • Esmira Arif Aga Quliyeva,
  • Mahammad Allahverdi Bayramov

摘要

Mononuclear complexes of Copper(II) with (E)-N′(3,5-di-tert-butyl-2-hydroxybenzili- dene)-2-hydroxybenzohydrazide (H3sahz)2, Cu(Hsahz)(H2O) and Cu(Hsahz)(DMF) were synthesized. The structure of the complexes was studied by elemental analysis, IR and EPR spectroscopy, and single-crystal X-ray analysis. It was shown that the complexes have a square-planar structure, in which the ligand is tridentate and dianionic. The coordination of Cu(II) ion is formed by the oxygen atom of the phenol group of 3,5-di-tert-butyl salicylic aldehyde, amidic oxygen atom is in enolic form, the oxygen atom of the DMF molecule and the nitrogen atom of the azomethine group. When recrystallizing from DMF/acetonitrile/ethanol = 1:2:4 solution, the water molecule in the complex is easily exchanged with the DMF molecule. The results of these studies showed that the complexes have a stronger antibacterial and antifungal effect than the ligand.