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<p>The review considers pivotal and novel research on developing organocatalysts that imitate key enzyme classes devoid of metal ions, such as lyases, hydrolases, transferases, and oxidoreductases. Special attention is paid to enantioselective transformations facilitated by organocatalysts. It is demonstrated that the development of enzyme mimetics has significant potential for the creation of new catalytic systems. Some classes of enzymes still have no analogues among organocatalysts.</p>

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Organocatalysts as Enzyme Mimetics: A Review

  • 期刊论文

  • 发表日期：

    2025年3月1日

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  • I. V. Komarov,
  • A. M. Hurieva,
  • V. I. Davydov,
  • A. Yu. Ishchenko,
  • O. O. Grygorenko

摘要

The review considers pivotal and novel research on developing organocatalysts that imitate key enzyme classes devoid of metal ions, such as lyases, hydrolases, transferases, and oxidoreductases. Special attention is paid to enantioselective transformations facilitated by organocatalysts. It is demonstrated that the development of enzyme mimetics has significant potential for the creation of new catalytic systems. Some classes of enzymes still have no analogues among organocatalysts.