<p>The operation of welded bimetallic structural elements of nuclear fusion equipment requires ensuring such properties as tightness, vacuum density, cyclic durability, resistance to thermal cycling, and other special service characteristics that cannot be obtained by fusion welding but can be obtained by explosive welding. A high-quality combination of different metal materials during explosion welding can be achieved due to the absence of significant heating and a thermal impact zone, which makes it possible to preserve the strength characteristics of metals and alloys and reduce the amount of intermetallics. The paper presents the results of studies of manufacturing pipe adapters from dissimilar materials, such as copper alloy + structural steel, using explosion welding. The adapter is a cylindrical bimetallic nozzle designed to connect pipelines of different metals using fusion welding. The paper considers the design features of a butt welded joint, called “quasi-butt”, which is obtained by assembling the adapter parts before explosion welding on surfaces with angular bevels. The paper describes the process of manufacturing adapters by explosion welding with their subsequent machining, which is promising for use in permanent joints of a wide range of metal materials. The explosive used was a mixture of ammonite 6ZhV and ammonium nitrate. The explosive was initiated using a piece of detonating cord DShe-12 and an electric detonator ED-8E. The developed modes of explosion welding ensured the production of a high-quality joint with a stable, smooth wave without melting. A batch of full-scale adapters was manufactured to implement an international project to create a fusion facility. Mechanical testing of the welded joints of the pipe adapters for static tensile strength, hardness, and vacuum density confirmed compliance with the requirements for welded nuclear fusion structures.</p>