<p>In the present paper, we designed a sensor to detect the cancer cells, employing the two metals on both sides of the analyte medium, which results a better sensing property. Designed structure consists of alternate layers of SiO<sub>2,</sub> TiO<sub>2</sub>, and after that an Ag metal placed to achieve the Tamm plasmon dip in the photonic bandgap. The structure was numerically calculated by using ANSYS Lumerical FDTD method. Designed sensor’s configuration was optimized for metal thickness and analyte layer thickness on the reflection spectrum. By selecting the optimized parameters, the structure achieves a high sensitivity, figure of merit and quality factor values. The present structure results a reflection dip at 1207.27&#xa0;nm for analyte medium of refractive index ‘1’ and results a full width at half maximum of 4.47&#xa0;nm. Obtained reflection spectrum clearly indicates the existence of Tamm plasmon. We have calculated the sensor capacity for normal cell and cancer effected cells. In the present paper we have studied various types of blood cell. For the normal blood-Jukart cell the structure shows a Tamm plasmon dip at 1190.26&#xa0;nm wavelength, and for cancer affected blood-Jukart cell the structure results Tamm plasmon dip at 1192.27&#xa0;nm wavelength, which results a shift of 2.01&#xa0;nm, skin-basal normal cell results Tamm plasmon dip at 1187.3&#xa0;nm wavelength and cancer affected skin-basal cell structure results at 1190.99&#xa0;nm wavelength which results a shift of 3.69&#xa0;nm Similarly, we have evaluated the Tamm plasmon dip for normal cell and for cancer affected cell for the following tissues such as cervical (Hela), adrenal gland (PC12), and breast (MDA-MB-231and MCF-7). Proposed design should be useful for biological sensing applications.</p>

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Design and Simulation of a DBR Structure based Tamm Plasmon Refractive Index Sensor for Cancer Cell Detection

  • Srinivas Sidhireddy,
  • Nandam Ashok

摘要

In the present paper, we designed a sensor to detect the cancer cells, employing the two metals on both sides of the analyte medium, which results a better sensing property. Designed structure consists of alternate layers of SiO2, TiO2, and after that an Ag metal placed to achieve the Tamm plasmon dip in the photonic bandgap. The structure was numerically calculated by using ANSYS Lumerical FDTD method. Designed sensor’s configuration was optimized for metal thickness and analyte layer thickness on the reflection spectrum. By selecting the optimized parameters, the structure achieves a high sensitivity, figure of merit and quality factor values. The present structure results a reflection dip at 1207.27 nm for analyte medium of refractive index ‘1’ and results a full width at half maximum of 4.47 nm. Obtained reflection spectrum clearly indicates the existence of Tamm plasmon. We have calculated the sensor capacity for normal cell and cancer effected cells. In the present paper we have studied various types of blood cell. For the normal blood-Jukart cell the structure shows a Tamm plasmon dip at 1190.26 nm wavelength, and for cancer affected blood-Jukart cell the structure results Tamm plasmon dip at 1192.27 nm wavelength, which results a shift of 2.01 nm, skin-basal normal cell results Tamm plasmon dip at 1187.3 nm wavelength and cancer affected skin-basal cell structure results at 1190.99 nm wavelength which results a shift of 3.69 nm Similarly, we have evaluated the Tamm plasmon dip for normal cell and for cancer affected cell for the following tissues such as cervical (Hela), adrenal gland (PC12), and breast (MDA-MB-231and MCF-7). Proposed design should be useful for biological sensing applications.