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<p>In this study, a photonic crystal-based biosensor has been designed to detect melanoma (ME) skin cancer cells. The proposed structure consists of multiple layers of metal and dielectric materials, and incorporates a cavity for cancer cell placement. The cavity thickness and other geometric parameters are optimized to achieve maximum sensitivity. The structure demonstrates an absorption rate of 99% within the wavelength range 750–900&#xa0;nm. The results indicate that the resonance wavelength depends on the geometric parameters and refractive index of the material. The results also reveal that the optimized sensor sensitivity is 378&#xa0;nm/RIU. Furthermore, the structure is cost-effective and offers relatively high sensitivity, making it a promising candidate for the timely detection of cancer cells. </p>

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Design and Performance Analysis of a Multilayer Photonic Crystal Biosensor for Enhanced Detection of Melanoma Skin Cancer

  • 期刊论文

  • 发表日期：

    2025年8月21日

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  • Fatemeh Kasraei,
  • Mehdi Hosseini

摘要

In this study, a photonic crystal-based biosensor has been designed to detect melanoma (ME) skin cancer cells. The proposed structure consists of multiple layers of metal and dielectric materials, and incorporates a cavity for cancer cell placement. The cavity thickness and other geometric parameters are optimized to achieve maximum sensitivity. The structure demonstrates an absorption rate of 99% within the wavelength range 750–900 nm. The results indicate that the resonance wavelength depends on the geometric parameters and refractive index of the material. The results also reveal that the optimized sensor sensitivity is 378 nm/RIU. Furthermore, the structure is cost-effective and offers relatively high sensitivity, making it a promising candidate for the timely detection of cancer cells.