A New Approach to Optical Biosensing Based on A One-Dimensional Quasi-Periodic Fibonacci Sequence
摘要
We have engineered a novel optical biosensor based on a one-dimensional quasi-periodic Fibonacci sequence, incorporating a nanocomposite material and titanium dioxide. The unique aspect of this design lies in the application of the quasi-periodic photonic crystal for detecting diseases like sickle cell anemia, HIV, and high cholesterol. Also, we use the nanocomposite material (low refractive index) with the titanium dioxide (high index) in the quasi-periodic structure. We have investigated the optical properties of the proposed design theoretically based on the well-known transfer matrix method and MATLAB tools near-infrared range. Additionally, we looked into how the Fibonacci sequence affected the suggested design’s optical characteristics. In addition, we used the suggested structure for the detection of high cholesterol, HIV-infected and sickle cell anemia in the blood samples based on making a cavity in the proposed design. Wherein, the blood sample is considered as a defect layer that contains normal and infected samples. Based on the change in the refractive indices of blood samples, there will be a shift in the position of the defect mode inside the resulting photonic band gap. Besides, some of the design parameters such as the volume fraction of nanocomposite material and the incident angle of the propagating electromagnetic wave are investigated to demonstrate their effects on the optical properties of the suggested design. The performance of the proposed biosensor design has been calculated, showing that the biosensor demonstrates high sensitivity, quality factor, detection accuracy, low detection limit, and sensor resolution, with values of 1228.94 nm/RIU, 5829.93325, 4.3976 (1/nm), 1.111 × 10–5 RIU, and 0.013496 nm, respectively.