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<p>The reaction of 2-aminobenzimidazole with iodomethyl ketones bearing aliphatic, aromatic, or heteroaromatic substituents was performed in a one-pot fashion under mild conditions, giving new 1,3-disubstitued 2-amino-1,3-benzimidazolium monoiodides and triiodides. The structures of the synthesized compounds were confirmed by <sup>1</sup>H NMR, <sup>13</sup>C NMR, IR, and UV spectroscopy and X-ray diffraction analysis.</p>

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Synthesis of 1,3-disubstituted 2-amino-1,3-benzimidazolium iodides and triiodides

  • 期刊论文

  • 发表日期：

    2026年1月1日

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  • N. O. Yarosh,
  • L. V. Zhilitskaya,
  • I. V. Sterkhova,
  • I. A. Dorofeev

摘要

The reaction of 2-aminobenzimidazole with iodomethyl ketones bearing aliphatic, aromatic, or heteroaromatic substituents was performed in a one-pot fashion under mild conditions, giving new 1,3-disubstitued 2-amino-1,3-benzimidazolium monoiodides and triiodides. The structures of the synthesized compounds were confirmed by 1H NMR, 13C NMR, IR, and UV spectroscopy and X-ray diffraction analysis.