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<p>New isothiouronium salts were synthesized by the reactions of thiourea with halo carboxylic acids in alcoholic media. The structures and composition of all synthesized compounds were confirmed by a complex of modern physical methods. The structure of one isothiouronium salt was established by X-ray diffraction analysis. The antimicrobial activity of the synthesized isothiouronium salts was evaluated <i>in vitro</i>.</p>

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New approach to the synthesis of isothiouronium salts based on halo carboxylic acids and thiourea

  • 期刊论文

  • 发表日期：

    2026年1月1日

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  • S. R. Romanov,
  • Yu. V. Bakhtiyarova,
  • H. Pak,
  • O. V. Orlova,
  • M. P. Shulaeva,
  • O. K. Pozdeev,
  • A. P. Fedonin,
  • O. N. Kataeva,
  • I. V. Galkina

摘要

New isothiouronium salts were synthesized by the reactions of thiourea with halo carboxylic acids in alcoholic media. The structures and composition of all synthesized compounds were confirmed by a complex of modern physical methods. The structure of one isothiouronium salt was established by X-ray diffraction analysis. The antimicrobial activity of the synthesized isothiouronium salts was evaluated in vitro.