<p>Novel synthetic approach to 3-quinazolinyl- and 3-quinoxalinyl-containing 7-aminocoumarins <i>via</i> nucleophilic substitution of hydrogen in the corresponding diazines has been developed. The proposed method employs readily available reagents and simple synthetic procedures without any catalysts based on the transition metals.</p>

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Nucleophilic substitution of hydrogen in benzodiazines via their reactions with 7-aminocoumarin

  • A. D. Sharapov,
  • R. F. Fatykhov,
  • I. A. Khalymbadzha,
  • A. P. Potapova,
  • E. M. Gurina,
  • Ya. K. Shtaitz,
  • D. S. Kopchuk,
  • G. V. Zyryanov

摘要

Novel synthetic approach to 3-quinazolinyl- and 3-quinoxalinyl-containing 7-aminocoumarins via nucleophilic substitution of hydrogen in the corresponding diazines has been developed. The proposed method employs readily available reagents and simple synthetic procedures without any catalysts based on the transition metals.