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<p>The application of carbocyanines with complexing groups as sensors for small molecules and metal ions is considered. Complexing carbocyanines capable of binding strongly and selectively to analytes to generate a reliable fluorescent response are promising for the development of sensor systems and study of cellular processes. The synthesis of new functionalized carbocyanines extends a possibility of detecting not only metals but also organic compounds in low concentrations, which is important for human health diagnostics and monitoring.</p>

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Carbocyanines with metal chelating groups as promising tools for diagnostics and therapy

  • 期刊论文

  • 发表日期：

    2025年8月1日

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  • I. A. Doroshenko,
  • N. V. Shmychkov,
  • A. O. Govtvan,
  • A. V. Shik,
  • M. K. Beklemishev,
  • T. A. Podrugina

摘要

The application of carbocyanines with complexing groups as sensors for small molecules and metal ions is considered. Complexing carbocyanines capable of binding strongly and selectively to analytes to generate a reliable fluorescent response are promising for the development of sensor systems and study of cellular processes. The synthesis of new functionalized carbocyanines extends a possibility of detecting not only metals but also organic compounds in low concentrations, which is important for human health diagnostics and monitoring.