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<p>Hydrogels based on copolymers of fish collagen and acrylates and obtained under conditions of visible light photocatalysis in the presence of complex oxide RbTe<sub>1.5</sub>W<sub>0.5</sub>O<sub>6</sub> were modified in several ways in order to preserve their major properties: three-dimensional structure and composition required for achieving the structural stability and the sizes of pores varying in a wide range from several to ∼70 µm. The chemical structure was described for the modified three-dimensional matrices, as well as their structural stability in weakly acidic and neutral solutions, water absorption, and pore sizes were measured. The explored objects met the requirements necessary to launch preclinical <i>in vitro</i> trials for hydrogel biocompatibility.</p>

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Some properties of matrices based on copolymers of fish collagen and acrylates designed for regenerative medicine and obtained under conditions of photocatalysisby visible light in the presence of RbTe1.5W0.5O6 oxide

  • 期刊论文

  • 发表日期：

    2025年5月1日

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  • L. L. Semenycheva,
  • V. O. Rumyantseva,
  • N. B. Valetova,
  • M. N. Egorikhina,
  • E. V. Suleimanov

摘要

Hydrogels based on copolymers of fish collagen and acrylates and obtained under conditions of visible light photocatalysis in the presence of complex oxide RbTe1.5W0.5O6 were modified in several ways in order to preserve their major properties: three-dimensional structure and composition required for achieving the structural stability and the sizes of pores varying in a wide range from several to ∼70 µm. The chemical structure was described for the modified three-dimensional matrices, as well as their structural stability in weakly acidic and neutral solutions, water absorption, and pore sizes were measured. The explored objects met the requirements necessary to launch preclinical in vitro trials for hydrogel biocompatibility.