Scholarlink

<p>The domino reaction of 2-(1-methyl-3-formylindol-4-yl)cyclopropane-1,1-dicarboxylate with benzylamines upon catalysis by gallium triflate gave two types of tetracyclic systems containing bridged azabicycles <i>peri</i>-annulated to the indole core. The reaction proceeded via the formation of intermediate imines, which underwent stepwise (3+2)-cross-cycloaddition reactions under conditions of the process, wherein the first step is the attack by the iminium nitrogen atom at either methylene or methine carbon atom of the small cycle.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Synthesis of bridged azaheterocycles peri-annulated to the indole core

  • 期刊论文

  • 发表日期：

    2025年1月1日

查看全文
  • S. M. Antropov,
  • S. A. Tokmacheva,
  • I. I. Levina,
  • I. V. Trushkov

摘要

The domino reaction of 2-(1-methyl-3-formylindol-4-yl)cyclopropane-1,1-dicarboxylate with benzylamines upon catalysis by gallium triflate gave two types of tetracyclic systems containing bridged azabicycles peri-annulated to the indole core. The reaction proceeded via the formation of intermediate imines, which underwent stepwise (3+2)-cross-cycloaddition reactions under conditions of the process, wherein the first step is the attack by the iminium nitrogen atom at either methylene or methine carbon atom of the small cycle.