Preparation of fluorinated 5,5′-dialkylsubstituted dipyrromethanes
摘要
A synthetic approach to novel fluorinated 5,5′-dialkyl-substituted dipyrromethanes based on acid-catalyzed condensation of the corresponding pyrroles and ketones was developed. High efficiency of this transformation for a wide range of pyrroles and ketones was demonstrated using trifluoromethanesulfonic acid as a catalyst. A series of novel fluorinated dipyrromethanes was obtained in high yields.