Synthesis of condensed dibenzo[b,f]pyrimido[1,6-d][1,4]oxazepines based on Biginelli products
摘要
A method for the synthesis of substituted dibenzo[b,f]pyrimido[1,6-d][1,4]oxazepines fused with the Biginelli products was proposed. This condensation was accomplished by the aromatic nucleophilic substitution reaction between 4,5-dichlorophthalonitrile or 4-bromo-5-nitrophthalonitrile and the salicylaldehyde-based Biginelli products.