Ti-catalyzed homocyclomagnesiation of (Z)-1,2,6-trienes in the stereoselective synthesis of 1Z,5Z,9Z,13Z-tetraenes
摘要
On the basis of the Ti-catalyzed homocyclomagnesiation of terminal 1,2-dienes, an effective method for the synthesis of 1Z,5Z,9Z,13Z-tetraenes in high yields and high stereoselectivity has been developed. A new approach to the synthesis of allenes with substituents containing Z-double bonds has been elaborated.