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Synthesis of 5-oxo-1-[4-(aminosulfonyl)phenyl]pyrrolidine-3-carboxylic acids

  • S. A. Serkov,
  • N. V. Sigay,
  • N. N. Kostikova,
  • A. P. Tyurin,
  • N. G. Kolotyrkina,
  • G. A. Gazieva

摘要

A series of new 1-[4-(aminosulfonyl)phenyl]-5-oxopyrrolidine-3-carboxylic acids were synthesized by the solvent-free condensation of 4-aminobenzenesulfonamides with itaconic acid at 140–165 °C. The synthesized compounds were examined for antimicrobial activity.