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Synthesis of spin-labeled bispidines

  • A. M. Zakirov,
  • A. V. Medved’ko,
  • I. I. Troshin,
  • E. V. Tretyakov,
  • S. Z. Vatsadze

摘要

Conjugates of bispidines and free radicals of the (2,2,6,6-tetramethylpiperidin-1-yl)-oxyl type were synthesized for the first time. The conjugates were obtained by the alkylation reaction of NH-bispidines with electrophilic chloro derivatives containing a free radical. The structure of the latter was established by X-ray diffraction analysis. The products obtained were characterized by IR spectroscopy, ESR spectroscopy, and high-resolution mass spectrometry.