4-Aryl(indol-3-yl)-2-pyrrolidone-3(5)-carboxamides: synthesis and structure

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发表日期：

2024年3月1日

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N. V. Gorodnicheva,
O. S. Vasil’eva,
E. S. Ostroglyadov,
R. I. Baichurin,
I. A. Litvinov,
S. V. Makarenko

摘要

The reaction of methyl 4-aryl(indol-3-yl)-2-pyrrolidone-3(5)-carboxylates with ammonia afforded racemic (3R*,4S*)-4-(indol-3-yl)-2-pyrrolidone-3-carboxamides and (4R*,5R*)-4-aryl-2-pyrrolidone-5-carboxamides. The three-dimensional structures of these compounds were determined by X-ray diffraction analysis.