Three-component reaction between phenanthridine, acetylenic ketones and bis(polyfluoroalkyl) H-phosphonates: synthesis of E-N-acylethenyl-6-bis(polyfluoroalkyl)phosphoryl-5,6-dihydrophenanthridines
摘要
A solvent-free three-component reaction between phenanthridine, acetylenic ketones, and bis(polyfluoroalkyl) H-phosphonates proceeded at room temperature for 20–24 h to stereoselectively give the corresponding E-N-acylethenyl-6-bis(polyfluoroalkyl)phosphoryl-5,6-dihydrophenanthridines in up to 82% yield.