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<p>In this study, the synthesis and characterization of hydroxyapatite (HAp)-supported CuO nanoparticles (CuO/HAp nanocatalyst) as an efficient and recyclable nanocatalyst were investigated for the synthesis of propargylamines. The CuO/HAp nanocatalyst was characterized using several analytical techniques, including FT-IR, XRD, FE-SEM, EDS, BET, and TGA. Antimicrobial properties of the CuO/HAp nanocatalyst were compared with those of copper oxide nanoparticles and hydroxyapatite alone, revealing superior antimicrobial activity on some gram-positive bacteria, gram-negative bacteria, and the fungal strain Candida albicans with better average OD. All reactions were conducted under solvent-free conditions, yielding corresponding products in high amounts. The CuO/HAp nanocatalyst exhibited excellent performance in the synthesis of propargylamines, and it can be recovered by simple filtration and recycled up to 4 following runs without any significant loss in its efficiency.</p>

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Hydroxyapatite-supported CuO nanoparticles: an efficient catalyst for the propargylamines synthesis with antimicrobial properties

  • 期刊论文

  • 发表日期：

    2025年4月4日

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  • Maryam Banitalebi,
  • Jalal Albadi,
  • Somayeh Shahrokh Shahraki

摘要

In this study, the synthesis and characterization of hydroxyapatite (HAp)-supported CuO nanoparticles (CuO/HAp nanocatalyst) as an efficient and recyclable nanocatalyst were investigated for the synthesis of propargylamines. The CuO/HAp nanocatalyst was characterized using several analytical techniques, including FT-IR, XRD, FE-SEM, EDS, BET, and TGA. Antimicrobial properties of the CuO/HAp nanocatalyst were compared with those of copper oxide nanoparticles and hydroxyapatite alone, revealing superior antimicrobial activity on some gram-positive bacteria, gram-negative bacteria, and the fungal strain Candida albicans with better average OD. All reactions were conducted under solvent-free conditions, yielding corresponding products in high amounts. The CuO/HAp nanocatalyst exhibited excellent performance in the synthesis of propargylamines, and it can be recovered by simple filtration and recycled up to 4 following runs without any significant loss in its efficiency.