<p>This study presents the preparation of bioactive curcumin immobilised double layered hydroxide nanoparticles (Mg–Al LDH and Zn–Al LDH). The materials were analysed by XRD, TEM, FTIR-ATR and PZC. An analysis of the equilibrium, kinetics and thermodynamics of the immobilisation process of curcumin was carried out to determine the most favourable parameters of the immobilisation process. The study also addressed the issue of increasing the sorption capacity of carriers by changing the solvent during the immobilisation process of curcumin, which shows limited solubility in water. The study confirmed that the type of carrier influences the immobilisation process of curcumin from ethanol by combining physical and chemical processes. The application of water during the immobilisation process in the case of the Mg–Al LDH material resulted in an increase in the sorption capacity of the material, achieving a higher immobilisation efficiency of curcumin (the sorption capacity increased from approximately 20&#xa0;mg/g curcumin from ethanol to 27&#xa0;mg/g curcumin in a 20% H₂O solution in ethanol). Process factors such as temperature, time, initial concentration of curcumin, type of solvent significantly affect the change in the immobilisation efficiency of curcumin on LDH. In the study, using the example of curcumin immobilisation, the possibility of depositing, with increased efficiency, water-insoluble compounds was confirmed, enabling their practical application as bioactive additives, among others.</p>