Catalytic performance of CuO/MgO nanocomposite for the regioselective synthesis of triazoles and investigation of antimicrobial activity

In this research, CuO/MgO nanocomposite was synthesized and characterized as a new, efficient and recyclable nanocatalyst, and then its catalytic activity was investigated on the regioselective synthesis of 1,4-disubstituted-1,2,3-triazole derivatives. The nanocatalyst was characterized by various methods, including XRD, FE-SEM, EDS, BET and TGA. Various triazole derivatives were synthesized from the reaction between propargyl ethers or terminal alkynes with aryl halides or alkyl halides with very good efficiency. Moreover, CuO/MgO nanocomposite was tested against six standard strains of bacteria to determine its antimicrobial activity. The results indicated that CuO/MgO nanocomposite had different levels of inhibition against different bacteria.