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Background <p>Patients with obesity who undergo metabolic bariatric surgery (MBS) may experience changes in health-related quality of life (HRQoL) at various time points. This study aimed to explore HRQoL trajectories during the first year post-surgery and identify associated factors in the early postoperative period.</p> Methods <p>A prospective, observational cohort study was conducted with 350 patients with severe (Class III) obesity, recruited through convenience sampling from two hospitals in southern Taiwan. HRQoL was assessed at 1 week, 1 month, 3 months, 6 months, and 12 months postoperatively via face-to-face interviews using the Impact of Weight on Quality of Life-Lite (IWQOL-Lite) questionnaire. Latent class growth analysis (LCGA) was employed to classify HRQoL trajectories, while multinomial logistic regression identified factors associated with each trajectory group.</p> Results <p>A total of 205 participants completed all five follow-up assessments. The mean overall HRQoL scores ranged from 55.8 (<i>SD</i> = 20.8) to 83.1 (<i>SD</i> = 16.3) throughout the study period. Three trajectory classes emerged: low starting (13.6%), medium starting (57.6%), and high starting (28.8%). Significant predictors of the low starting trajectory included older age, female, single marital status, college education or higher, body weight one week post-surgery, and the percentage of total weight loss (%TWL) one week after surgery.</p> Conclusions <p>Patients’ HRQoL generally improved gradually over the first year after surgery. Special attention should be given to the IWQOL-Lite scores of female patients, those with a college education or higher, older individuals, and those who had higher weight and depression scores one week after surgery.</p>

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Impact of body weight on quality of life trajectories following metabolic bariatric surgery in individuals with obesity: a longitudinal study

  • 期刊论文

  • 发表日期：

    2026年3月13日

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  • Shu-Fen Wu,
  • Ruey-Hsia Wang,
  • Tien-Chou Soong,
  • Yen-Hao Su,
  • Shu-Fen Wung,
  • Pei-Chao Lin

摘要

Background

Patients with obesity who undergo metabolic bariatric surgery (MBS) may experience changes in health-related quality of life (HRQoL) at various time points. This study aimed to explore HRQoL trajectories during the first year post-surgery and identify associated factors in the early postoperative period.

Methods

A prospective, observational cohort study was conducted with 350 patients with severe (Class III) obesity, recruited through convenience sampling from two hospitals in southern Taiwan. HRQoL was assessed at 1 week, 1 month, 3 months, 6 months, and 12 months postoperatively via face-to-face interviews using the Impact of Weight on Quality of Life-Lite (IWQOL-Lite) questionnaire. Latent class growth analysis (LCGA) was employed to classify HRQoL trajectories, while multinomial logistic regression identified factors associated with each trajectory group.

Results

A total of 205 participants completed all five follow-up assessments. The mean overall HRQoL scores ranged from 55.8 (SD = 20.8) to 83.1 (SD = 16.3) throughout the study period. Three trajectory classes emerged: low starting (13.6%), medium starting (57.6%), and high starting (28.8%). Significant predictors of the low starting trajectory included older age, female, single marital status, college education or higher, body weight one week post-surgery, and the percentage of total weight loss (%TWL) one week after surgery.

Conclusions

Patients’ HRQoL generally improved gradually over the first year after surgery. Special attention should be given to the IWQOL-Lite scores of female patients, those with a college education or higher, older individuals, and those who had higher weight and depression scores one week after surgery.