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Purpose <p>To identify and synthesize evidence from European qualitative studies on cancer-related quality of life outcomes, needs, experiences, preferences, and concerns of people undergoing cancer treatment in the last decade.</p> Methods <p>Systematic review (<a href="https://www.crd.york.ac.uk/PROSPERO">https://www.crd.york.ac.uk/PROSPERO</a>, CRD42024575065) of European studies using qualitative methodology, assessing constructs related to HRQoL, and involving adults receiving cancer treatment. The search was performed in PubMed and Scopus from January 2013 to July 2024. Titles, abstracts, and full texts screening, data extraction and risk of bias assessment were conducted independently by two researchers. The main outcomes were the themes reported in each study. The thematic analysis was performed by organizing the themes of the studies into categories.</p> Results <p>Out of 18,256 articles initially identified, 36 met the inclusion criteria: 21 with generic and 15 with specific objectives. Five categories encompassing 110 themes were identified from the generic studies: Psychological Function (n = 41), Clinical Management (n = 26), Symptoms and Physical Function (n = 18), Social Function (n = 16), and Life Disruption (n = 9). Eleven studies with specific objectives focused on clinical management with all their themes fitting within the categories identified in the generic studies.</p> Conclusions <p>Results showed the predominance of psychological function and clinical management themes. Symptoms and physical function, social function, and life disruption maintained their importance within the classical HRQoL framework. The emergence of clinical management is consistent with the growing patient-centered care approach, suggesting the need to integrate this content into the evaluation of patients undergoing cancer treatment. Limitations: most European countries were not represented, and publication bias could hide traditional domains.</p>

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Health-related quality of life domains relevant to people in Europe undergoing cancer treatment: a systematic review of qualitative research

  • 期刊论文

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  • 发表日期：

    2026年5月14日

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  • Catalina Lizano-Barrantes,
  • Clara Amat-Fernandez,
  • Olatz Garin,
  • Yolanda Pardo,
  • Óscar Périz-Colón,
  • Pablo Notti Saint-Jean,
  • Leslye Rojas-Concha,
  • Melissa Thong,
  • Giovanni Apolone,
  • Cinzia Brunelli,
  • Augusto Caraceni,
  • Norbert Couespel,
  • Nanne Bos,
  • Mogens Groenvold,
  • Stein Kaasa,
  • Gennaro Ciliberto,
  • Claudio Lombardo,
  • Ricardo Pietrobon,
  • Gabriella Pravettoni,
  • Aude Sirven,
  • Hugo Vachon,
  • Alexandra Gilbert,
  • Galina Velikova,
  • Montse Ferrer,
  • Massimo Costantini,
  • Madeline Pe,
  • Galina Velikova,
  • Chiara Marzorati,
  • Antonio Tanzilli,
  • Morten Aagaard Petersen,
  • Olatz Garin,
  • Aline Machiavelli,
  • Joachim Widder,
  • Helidon Nina,
  • Philip Debruyne,
  • Ivaylo Petrov,
  • Vesna Ramljak,
  • Maria Krini,
  • Tomas Kazda,
  • Helle Pappot,
  • Liina Pääbo,
  • Vahur Valvere,
  • Johanna Mattson,
  • Ann Bredart,
  • Carole Boulec,
  • Mariaalice Borinelli-Franzoi,
  • Ekaterina Kldiashvili,
  • Christian Brandts,
  • Nicole Erickson,
  • Volker Arndt,
  • Olga Balaoura,
  • Horvath Orsolya,
  • Claire Donohoe,
  • Alessandro Rizzo,
  • Andrea Pace,
  • Sandra Lejniece,
  • Audrius Dulskas,
  • Vadim Pogonet,
  • Lonneke van de Poll,
  • Marianne Grønlie Guren,
  • Iwona Ługowska,
  • Maria Litwiniuk,
  • Maria José Bento,
  • Tudor Ciuleanu,
  • Milana Mitrić,
  • Ivica Ratosa,
  • Michal Chovanec,
  • Maria Vieito,
  • Héctor Aguilar,
  • Eva Ruiz,
  • Karin Ahlberg,
  • Eda Tanrikulu Simsek,
  • Mahmut Gumus,
  • Inke Minnée-van Braak,
  • Caitriona Higgins,
  • Laura Pinnavaia,
  • Carina Dantas,
  • Tapani Kalmi,
  • Leslye Rojas-Concha

摘要

Purpose

To identify and synthesize evidence from European qualitative studies on cancer-related quality of life outcomes, needs, experiences, preferences, and concerns of people undergoing cancer treatment in the last decade.

Methods

Systematic review (https://www.crd.york.ac.uk/PROSPERO, CRD42024575065) of European studies using qualitative methodology, assessing constructs related to HRQoL, and involving adults receiving cancer treatment. The search was performed in PubMed and Scopus from January 2013 to July 2024. Titles, abstracts, and full texts screening, data extraction and risk of bias assessment were conducted independently by two researchers. The main outcomes were the themes reported in each study. The thematic analysis was performed by organizing the themes of the studies into categories.

Results

Out of 18,256 articles initially identified, 36 met the inclusion criteria: 21 with generic and 15 with specific objectives. Five categories encompassing 110 themes were identified from the generic studies: Psychological Function (n = 41), Clinical Management (n = 26), Symptoms and Physical Function (n = 18), Social Function (n = 16), and Life Disruption (n = 9). Eleven studies with specific objectives focused on clinical management with all their themes fitting within the categories identified in the generic studies.

Conclusions

Results showed the predominance of psychological function and clinical management themes. Symptoms and physical function, social function, and life disruption maintained their importance within the classical HRQoL framework. The emergence of clinical management is consistent with the growing patient-centered care approach, suggesting the need to integrate this content into the evaluation of patients undergoing cancer treatment. Limitations: most European countries were not represented, and publication bias could hide traditional domains.