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<p>Plants play a crucial role in traditional medicine.&#xa0;Several medicinal plants have been utilized in traditional medicine preparations for centuries, and many of these formulations are still in use. The genus <i>Magnolia</i> L. (Family Magnoliaceae Juss.) has numerous medicinally significant species, the majority of which are endemic to Asia. Many species in this genus have traditionally been used to cure a wide range of conditions, from minor illnesses to advanced malignancies. Because of their adaptable therapeutic characteristics, various species from this genus have been blended and employed in commercially successful pharmaceutical formulations. Many investigations on phytochemistry, pharmacology, and toxicology have shown that the compounds honokiol, magnolol, liriodenine, and anonaine have beneficial therapeutic qualities for a variety of diseases. Besides, researchers have announced many new compounds with interesting bioactivities. This review focuses on the results of <i>Magnolia</i> metabolite research undertaken during this time period (2003–2023). Pharmacological investigations on substances from this genus are also mentioned. In addition, traditional applications are briefly discussed.</p> Graphical abstract <p></p>

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Phytochemistry and biological activities of Magnolia genus: from 2003 to 2023

  • 期刊论文

  • 发表日期：

    2025年4月22日

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  • Pham Van Huyen,
  • Nguyen Thi Thu Hien,
  • Tran Thi Ngoc Hanh,
  • Nguyen Huu Huong Duyen,
  • Nguyen Thi Dieu Thuan,
  • Nguyen Huu Toan Phan

摘要

Plants play a crucial role in traditional medicine. Several medicinal plants have been utilized in traditional medicine preparations for centuries, and many of these formulations are still in use. The genus Magnolia L. (Family Magnoliaceae Juss.) has numerous medicinally significant species, the majority of which are endemic to Asia. Many species in this genus have traditionally been used to cure a wide range of conditions, from minor illnesses to advanced malignancies. Because of their adaptable therapeutic characteristics, various species from this genus have been blended and employed in commercially successful pharmaceutical formulations. Many investigations on phytochemistry, pharmacology, and toxicology have shown that the compounds honokiol, magnolol, liriodenine, and anonaine have beneficial therapeutic qualities for a variety of diseases. Besides, researchers have announced many new compounds with interesting bioactivities. This review focuses on the results of Magnolia metabolite research undertaken during this time period (2003–2023). Pharmacological investigations on substances from this genus are also mentioned. In addition, traditional applications are briefly discussed.

Graphical abstract