Insights into Pinus species: phytochemistry, pharmacology and industrial potential of Indian Pinus species
摘要
The Pinus species of Indian Himalayan Region have a plethora of pharmacological attributes due to the presence of secondary metabolites in various plant parts such as needle, bark, wood, and cone. Pinus species fall under the purview of both traditional medicine and modern pharmacology. Notably, five indigenous pine species thrive in the Indian Himalayas: (1) Pinus gerardiana, (2) Pinus roxburghii , (3) Pinus wallichiana, (4) Pinus merkusii and (5) Pinus kesiya. These species produce large number of specialized metabolites, including terpenes, polyphenols, flavonoids, alkaloids and tannins, demonstrating efficacy against asthma, cancer, liver and kidney disorders, inflammation, as well as in various antimicrobial diseases. The Pinus species are also known for the extraction of oleoresin composed of rosin and turpentine. The improved chemical processing such as hydration, hydrogenation, oxidation, isomerization, and esterification of various compounds present in oleoresin yielded a variety of compounds used in the pharmaceutical, perfumery, cosmetic, paint, varnish, adhesive and various other industries. This review aims to accentuate the distribution, biosynthetic pathways, phytochemistry, pharmacology and industrial applications of Pinus species found in India.