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<p>The genus <i>Salvia</i> belongs to the Lamiaceae family and is widely distributed worldwide, including about 1000 accepted species. Traditionally, <i>Salvia</i> spp. have been used to treat several ailments, including digestive disorders, inflammations, and skin disorders. In Greece, 25 <i>Salvia</i> taxa (species and subspecies) occur in different areas. In-depth research of previously published literature was performed on electronic databases with several key search words for the collection of the available data focused on the phenolic constituents of Greek native <i>Salvia</i> taxa. A total of 109 scientific studies have been used since 2002. Overall, 21 Greek native <i>Salvia</i> taxa have been studied with <i>S. officinalis</i> being the most extensively researched. So far, 251 fully elucidated chemical structures of phenolic constituents from native Greek <i>Salvia</i> taxa were reported, including phenolic acids/caffeic acid derivatives, flavonoids and biosynthetically related metabolites, flavonolignans and lignans, coumarins, phenylethanoid/phenylpropanoid glycosides and other constituents. This review summarizes and discusses the current knowledge of the phenolic content of <i>Salvia</i> plants, revealing the uncharted scientific territory and may provide critical information for future perspectives on these valuable plants.</p> Graphical abstract <p></p>

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Phenolic constituents of Greek native Salvia species: a comprehensive review

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年3月19日

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  • Maria Anagnostou,
  • Ekaterina-Michaela Tomou,
  • Nikos Krigas,
  • Helen Skaltsa

摘要

The genus Salvia belongs to the Lamiaceae family and is widely distributed worldwide, including about 1000 accepted species. Traditionally, Salvia spp. have been used to treat several ailments, including digestive disorders, inflammations, and skin disorders. In Greece, 25 Salvia taxa (species and subspecies) occur in different areas. In-depth research of previously published literature was performed on electronic databases with several key search words for the collection of the available data focused on the phenolic constituents of Greek native Salvia taxa. A total of 109 scientific studies have been used since 2002. Overall, 21 Greek native Salvia taxa have been studied with S. officinalis being the most extensively researched. So far, 251 fully elucidated chemical structures of phenolic constituents from native Greek Salvia taxa were reported, including phenolic acids/caffeic acid derivatives, flavonoids and biosynthetically related metabolites, flavonolignans and lignans, coumarins, phenylethanoid/phenylpropanoid glycosides and other constituents. This review summarizes and discusses the current knowledge of the phenolic content of Salvia plants, revealing the uncharted scientific territory and may provide critical information for future perspectives on these valuable plants.

Graphical abstract