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<p>The constituent compositions of essential oils from herbs of common yarrow (<i>Achillea millefolium</i> L.), cartilaginous yarrow (<i>Achillea cartilaginea</i> Ledeb. ex Rchb.), and noble yarrow (<i>Achillea nobilis</i> L.) were comparatively studied by gas-chromatography(mass-spectrometry (GC-MS) and spectrophotometry. It was determined using GC-MS that the samples of essential oils from herbs of the studied <i>Achillea</i> species were characterized by high contents of mono- and bicyclic monoterpenes, among which common constituents were eucalyptol (cineole), caryophyllene oxide, β-pinene, α-terpineol, 4-terpineol, ã-terpinene, camphene, and β-cubenene. However, the fundamental difference between essential oils was the level of chamazulene contents: in <i>A. millefolium</i>, 7.53%; in <i>A. cartilaginea</i>, 0.22%; and in <i>A. nobilis</i>, absent. It was also determined that the content of proazulenes in <i>A. millefolium</i> herb was significantly higher than those in <i>A. cartilaginea</i> and <i>A. nobilis</i> (0.0411, 0.0012, and 0.0015%, respectively), although the non-pharmacopoeial <i>Achillea</i> species differed in a higher content of essential oil. Consequently, the results of the conducted studies indicated the expediency of standardization of <i>Achillea</i> herbs not only in terms of the contents of essential oil and total flavonoids, but also in terms of the contents of proazulenes, which determine the anti-inflammatory properties of preparations of this raw material.</p>

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Comparative Study of the Constituent Composition of Essential Oil from Herb Species of the Genus Achillea L.

  • 期刊论文

  • 发表日期：

    2025年4月1日

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  • V. A. Kurkin,
  • A. I. Vaskova,
  • T. K. Ryazanova

摘要

The constituent compositions of essential oils from herbs of common yarrow (Achillea millefolium L.), cartilaginous yarrow (Achillea cartilaginea Ledeb. ex Rchb.), and noble yarrow (Achillea nobilis L.) were comparatively studied by gas-chromatography(mass-spectrometry (GC-MS) and spectrophotometry. It was determined using GC-MS that the samples of essential oils from herbs of the studied Achillea species were characterized by high contents of mono- and bicyclic monoterpenes, among which common constituents were eucalyptol (cineole), caryophyllene oxide, β-pinene, α-terpineol, 4-terpineol, ã-terpinene, camphene, and β-cubenene. However, the fundamental difference between essential oils was the level of chamazulene contents: in A. millefolium, 7.53%; in A. cartilaginea, 0.22%; and in A. nobilis, absent. It was also determined that the content of proazulenes in A. millefolium herb was significantly higher than those in A. cartilaginea and A. nobilis (0.0411, 0.0012, and 0.0015%, respectively), although the non-pharmacopoeial Achillea species differed in a higher content of essential oil. Consequently, the results of the conducted studies indicated the expediency of standardization of Achillea herbs not only in terms of the contents of essential oil and total flavonoids, but also in terms of the contents of proazulenes, which determine the anti-inflammatory properties of preparations of this raw material.