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<p>The extraction mode of <i>Orostachys spinosa</i> herb has been optimized. Adry extract of <i>O. spinosa</i> has been obtained. The amino-acid compositions of the herb and extract of <i>O. spinosa</i> were determined. The extracts of the aerial parts of <i>O. spinosa</i> and the dry extract contained eight free amino acids, including the essential amino acids phenylalanine, arginine, lysine and, methionine; 15 bound amino acids, including the essential amino acids arginine, valine, lysine, methionine, and phenylalanine. The predominant amino acids were alanine, lysine and leucine. The neuroprotective activity of the <i>O. spinosa</i> extract was established in animal experiments against the background of hypoxic conditions.</p>

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Amino-Acid Composition and Neuroprotective Activity of the Extract of Orostachys spinosa

  • 期刊论文

  • 发表日期：

    2025年1月1日

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  • I. G. Nikolaeva,
  • Ya. G. Razuvaeva,
  • A. A. Toropova,
  • L. P. Tsybiktarova,
  • G. G. Nikolaeva,
  • N. V. Danzhalova,
  • E. A. Bayandueva

摘要

The extraction mode of Orostachys spinosa herb has been optimized. Adry extract of O. spinosa has been obtained. The amino-acid compositions of the herb and extract of O. spinosa were determined. The extracts of the aerial parts of O. spinosa and the dry extract contained eight free amino acids, including the essential amino acids phenylalanine, arginine, lysine and, methionine; 15 bound amino acids, including the essential amino acids arginine, valine, lysine, methionine, and phenylalanine. The predominant amino acids were alanine, lysine and leucine. The neuroprotective activity of the O. spinosa extract was established in animal experiments against the background of hypoxic conditions.