Spatial Structure and Anti-Inflammatory Activity of 5-N-Arylaminocarbonyl-6-Aryl-4-Methyl-1,2,3,6-Tetrahydropyrimidine-2-Thiones
摘要
The anti-inflammatory activity of 17 derivatives of 5-N-arylaminocarbonyl-6-aryl-4-methyl-1,2,3,6-tetrahydropyrimidine-2-thiones was studied. The molecular structure of one of them was established. Ten compounds that inhibited the inflammatory reaction in experimental animals in the range 56-81% were identified.