Modernization of the Synthesis and Anti-Inflammatory Activity of 4,10-di(2-Ethoxyacetyl)-2,6,8,12-Tetraacetyl-2,4,6,8,10,12-Hexaazaisowurtzitane – An Innovative Non-Narcotic Analgesic

期刊论文
发表日期：

2024年2月1日

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V. V. Eremina,
D. A. Kulagina,
S. G. Krylova,
E. A. Kiseleva,
T. N. Povetyeva,
E. P. Zueva,
N. I. Suslov,
S. V. Sysolyatin,
V. V. Zhdanov

摘要

A modified method for the synthesis of a promising non-narcotic analgesic agent of the hexaazaisowurtzitane class with pronounced anti-inflammatory activity is described. Methods for reducing the cost of the target substance are considered. The physicochemical characteristics are described. The efficacy and safety of the synthesized agent are shown in several animal models.