Chloroacetates of Substituted 1H-Indol-5-,6-,7-Ylamines and Their Antimicrobial Activity
摘要
Water-soluble 1H-indol-5-, 6-, 7-ylammonium chloroacetates were obtained from the reaction of substituted 1H-indol-5-, 6-, 7-ylamines with chloroacetic acid; identified based on PMR, UV, and mass spectra; and screened in the laboratory for antimicrobial activity. All the tested compounds could suppress the growth of microorganism test strains at various minimum inhibitory concentrations (MICs). The MIC values were observed to depend on the nature and pattern of substitution on the indole system.