<p>Many designed sensors these days identify only one specific virus creating practical healthcare limitation in real-world, as it will be more effective to detect multiple viruses for faster and more comprehensive diagnosis. This research work focused on to develop a rapid, label-free, highly accurate and cost-effective sensor device for multiple virus detection, for rapid diagnosis and improved patient care. This work presents a metamaterial based sensor for the detection of various viruses. The novel design composed of two identical semi-circle resonators on the top and polyimide as a dielectric layer in the middle. The simulations results illustrate three resonance peaks with absorption rates greater than 95% in detection frequency range from 0.6 to 3 THz. Moreover, the proposed design has been investigated for sensing performance by altering the refractive index of surrounding medium. The suggested sensor displays high Q factor, high sensitivity and Figure of merit with maximum values are 284.3, 0.86 THz/ RIU and 107.5 RIU⁻¹ in the investigating range of 1 to 1.5. This enhanced sensitivity allows the sensor to effectively detect multiple viruses including malaria, dengue, influenza A, immune deficiency syndrome (AIDS) and corona. Our findings demonstrate that this sensor holds great potential for diverse sensing applications, making it as a highly promising candidate for next-generation biosensing.</p>