Scholarlink

<p>The mechanisms of the emergence, existence, and functioning of receptor clusters formed on the surfaces of nerve cells are considered. Both experimental data and model concepts describing and explaining these processes are presented. The roles of cholesterol, extracellular proteins, and the perimembrane cytoskeleton in the formation and maintenance of the structure of receptor clusters is discussed. In the cases of ionotropic glutamate and acetylcholine receptors, the possibility of increasing the sensitivity of neurons to mediators due to cooperative activation, when closely located receptors and channels of the same cluster influence each other’s activity, is considered.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Clustering and Interactions of Ionotropic Receptors – Processes, Mechanisms, Basis of Plasticity

  • 期刊论文

  • 发表日期：

    2026年8月3日

查看全文
  • G. B. Murzina

摘要

The mechanisms of the emergence, existence, and functioning of receptor clusters formed on the surfaces of nerve cells are considered. Both experimental data and model concepts describing and explaining these processes are presented. The roles of cholesterol, extracellular proteins, and the perimembrane cytoskeleton in the formation and maintenance of the structure of receptor clusters is discussed. In the cases of ionotropic glutamate and acetylcholine receptors, the possibility of increasing the sensitivity of neurons to mediators due to cooperative activation, when closely located receptors and channels of the same cluster influence each other’s activity, is considered.