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<p>The combination of amyotrophic lateral sclerosis (ALS) and Alzheimer’s disease is rare. At present, it is unclear whether this comorbidity is a coincidence or a manifestation of a specific pathological process. A case of the simultaneous development of the classical symptoms of the bulbar form of ALS and Alzheimer’s disease is presented. Possible mechanisms of the combination of the two diseases are analyzed.</p>

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Combination of Amyotrophic Lateral Sclerosis with Alzheimer’s Disease

  • 期刊论文

  • 发表日期：

    2026年8月3日

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  • E. V. Pervushina,
  • M. A. Kutlubaev,
  • D. R. Kuznetsova,
  • G. I. Karimova,
  • O. V. Kachemaeva,
  • E. A. Mkhitaryan

摘要

The combination of amyotrophic lateral sclerosis (ALS) and Alzheimer’s disease is rare. At present, it is unclear whether this comorbidity is a coincidence or a manifestation of a specific pathological process. A case of the simultaneous development of the classical symptoms of the bulbar form of ALS and Alzheimer’s disease is presented. Possible mechanisms of the combination of the two diseases are analyzed.