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<p><b>Objective.</b> To assess the prevalence and clinical features of mal de débarquement syndrome (from the French for disembarkation syndrome; MdDS) in patients with dizziness and comorbidity with other vestibular and neurological disorders. <b>Materials and methods.</b> The study included 2738 patients (77.7% women) aged 18–70 years who were followed in the Otolaryngology Department of the Peter the Great Clinical Hospital of the I. I. Mechnikov North-Western State Medical University from 2023 to 2024. Investigations included neuroimaging, electroencephalography, duplex scanning of the head and neck vessels, and neurological and otoneurological examination. <b>Results.</b> The commonest form of dizziness is benign paroxysmal postural vertigo (BPPV), the second most common is vestibular paroxysmia, and the third is Ménière’s disease. Dizziness in many patients, was due to combinations of multiple diseases. A quarter of the patients had complications in the form of persistent postural perceptual dizziness (PPPD). PPPD was a complication of previous episodes of peripheral and central dizziness, but most often developed in patients with MdDS. MdDS was associated with vestibular paroxysmia (38.9%), BPPV (11.1%), and vestibular migraine (5.6%). A clinical case of a patient with MdDS is presented. <b>Conclusions.</b> MdDS is a rare condition whose diagnosis requires exclusion of other forms of dizziness. Application of a set of diagnostic tests allows correct diagnoses to be made and the right treatment tactics to be selected.</p>

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Mal de Débarquement Syndrome – a Poorly Understood and Rare Condition in Clinical Practice

  • 期刊论文

  • 发表日期：

    2026年7月27日

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  • L. M. Mirzaeva,
  • V. A. Voronov,
  • K. N. Akhmedova,
  • D. Yu. Demidenko,
  • A. O. Konstantinov

摘要

Objective. To assess the prevalence and clinical features of mal de débarquement syndrome (from the French for disembarkation syndrome; MdDS) in patients with dizziness and comorbidity with other vestibular and neurological disorders. Materials and methods. The study included 2738 patients (77.7% women) aged 18–70 years who were followed in the Otolaryngology Department of the Peter the Great Clinical Hospital of the I. I. Mechnikov North-Western State Medical University from 2023 to 2024. Investigations included neuroimaging, electroencephalography, duplex scanning of the head and neck vessels, and neurological and otoneurological examination. Results. The commonest form of dizziness is benign paroxysmal postural vertigo (BPPV), the second most common is vestibular paroxysmia, and the third is Ménière’s disease. Dizziness in many patients, was due to combinations of multiple diseases. A quarter of the patients had complications in the form of persistent postural perceptual dizziness (PPPD). PPPD was a complication of previous episodes of peripheral and central dizziness, but most often developed in patients with MdDS. MdDS was associated with vestibular paroxysmia (38.9%), BPPV (11.1%), and vestibular migraine (5.6%). A clinical case of a patient with MdDS is presented. Conclusions. MdDS is a rare condition whose diagnosis requires exclusion of other forms of dizziness. Application of a set of diagnostic tests allows correct diagnoses to be made and the right treatment tactics to be selected.